The conference will consist of an opening ceremony on the 3rd September followed by three full days of talks, poster presentations and opportunity to interact. Our preliminary programme is such that days will be delivered in the following format (subject to change)-

ISRA2017- Sunday evening Plenary: 6-7 pm.

Mark Nelson: “Vascular Control

Chair I. Greenwood

Registration Desk Open:

Sunday 5-6pm

Monday 7-8am

Tuesday 7-8am

Wednesday 7-8am


Monday 4th

Tuesday 5th

Wednesday 6th


SESSION 1: Channels & Exchangers

Chairs: I. Greenwood  & K. Sward

SESSION 1: Regulation

Chairs: T.  Jepps & A.  McNeish

SESSION 1: Structural

Chair: J. Jaggar &  Bodtkjer


J. Jaggar (USA) – Blood pressure regulation by PKD2 (TRPP1 ) channels


A. Albert (UK) –          Regulation of voltage-gated Ca2+ channels and vascular contractility by MARCKS


E. Boedtker (Denmark)-Transport and sensing of HCO3– modify resistance artery function: consequences for blood pressure and metabolic regulation of tone


 B. Isakson (USA) – Pannexin1 and sympathetic control of the vasculature

T. Haas (Canada)- Modulation of angiogenesis by anti-angiogenic factors


K. Sward (Sweden)- Notch provides a constitutive drive for expression of soluble guanylyl cyclase in the vascular wall that is inhibited by  hypertension


M Cipolla (USA) – Regulation of vascular resistance in the brain: Physiology and          pathophysiology


Y Wang (Hong Kong) – SIRT1 expression and vascular ageing

M. Navedo (USA) -Purinergic signaling in diabetic resistance arteries


M. Mederos Y Schnitzler (Germany)- The role of GPCRs for mechanosensation in arteries


T. Jepps (Denmark) – Regulation of arterial tone by ancillary KCNE  subunits



L. Martinez-Lemus (USA) –
Relationships between cell adhesion and vascular smooth muscle cytoskeletal structures in arteriolar vasoconstriction and remodeling.








SESSION 2: Interaction other cells

Chairs: S. Sandow & Isakson

SESSION 2: Interaction other cells

Chairs: T. Longden & J. Lopez-Lopez

SESSION 2: Interaction other cells

Chairs: S. Withers & T. Murphy


T. Longden  (USA) –   Capillary-to-arteriole communication regulates blood flow into the brain


C. Tran (Canada)- Alteration to cerebral hemodynamics modifies astrocytes Ca2+ activity in awake, behaving mice


C. Hall (UK) – Regulation of cerebral blood flow by pericytes


G. Whitely (UK) – Spiral artery remodeling in early pregnancy

L. Santana (USA)-Local control of vascular smooth muscle



A. Hobbs (UK) –     Pivotal vascular homeostatic role for        endothelium – derived C-type natriuretic peptide.



G. Drummond (Australia) – B cell mediated immunity and hypertension


From submissions
Lucia Alonso-Carbajo, Yeranddy Aguiar Alpizar, Justyna Startek, Jose Ramon Lopez-Lopez, Maria Teresa Perez-Garcia and Karel Talavera -TRPM3 dependent-vasodilation in resistance arteries (EC)
Makhala M. Khammy, Avelino Ferreira , Christian Aalkjær – [Ca2+] changes in axons in rat mesenteric arteries: relation to noradrenaline release and contraction (EC)

M.  Fernández-Alfonso (Spain)-Regional differences in perivascular adipose tissue impacting vascular homeostasis


E Eringa (Amsterdam)-Inflammation of         perivascular adipose tissue as a driver of microvascular dysfunction in obesity and  prediabetes.


M De Silva (Australia) –
Activation of the Brain Renin Angiotensin System Selectively Impairs Cerebrovascular Function


S Davidge (Canada) – Pregnancy complications and programming of vascular dysfunction in adult offspring







Free time

Free time

Plenary Speaker 13.30-14.30

U. Pohl-A hitchhikers guide to the ISRA galaxy

 Chair: C. Aalkjaer

From Submissions       14.45-15.45

Chairs: J De Mey  &  Y. Alexander

From Submissions

S Saxton (UK) – Mechanisms of perivascular adipose tissue dysfunction in obesity and restoration using exercise (EC)
Ahmed M. Hashad, Osama F. Harraz, Suzanne E. Brett, Mario Kassmann, Maik Gollasch, Donald G. Welsh – Caveolae Couple CaV3.2 to Ca2+ spark and STOC Production in Vascular Smooth Muscle (EC)
Timothy V. Murphy, T. Hilton Grayson, Shaun L. Sandow – Interaction between pressure-induced myogenic tone and TRPV4-mediated vasodilation in the rat cremaster muscle artery


Moderated posters and vendors

Moderated posters and vendors






Special: C.  Aalkjaer – The remarkable hemodynamic system of giraffes

 Chair: C. de Vit

Special: R Touyz – Vessels at the heart of hypertension

Chair: T. Heagerty


SESSION 3: Clinical scenarios

Chairs: Gusik

SESSION 3: Clinical scenarios

Chairs: Briones


H. Li (Germany) – Role of perivascular adipose tissue in obesity-induced vascular    dysfunction


D.  Stepp  (USA) -Novel mechanisms of altered vasomotor tone in obesity


A. Briones (Spain) – Novel mechanisms of vascular damage in hypertension

M. Bennett (UK) – Life, death and old age : role of vascular smooth muscle cells in                atherosclerosis


 T. Guzik  (UK)-Inflammation as a therapeutic target in hypertension and vascular dysfunction


From submissions
C. Stæhr, R. Rajanathan, S. Sandow, C. Aalkjaer, V. Matchkov – K+ transport abnormalities in cerebral arteries disturb neurovascular coupling in Familial Hemiplegic Migraine type 2 (FHM2) (EC)
Jo G. R. De Mey, Thomas M. Leurgans, Katrine Nissen, Susanne Hansen, Inger Nissen, Kristoffer Rosenstand, Akhmadjon Irmukhamedov, Lars P. Riber, Lars M. Rasmussen, Maria Bloksgaard – Media-to-lumen ratio and contractility of resistance arteries from cardiovascular disease patients

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